The link between dietary fats and heart health can feel complicated, especially with mixed messages about what to eat.
Despite this confusion, the research is consistent on one key point: increasing your intake of unsaturated fats is one of the simplest and most effective ways to improve heart health.
Instead of focusing on what to avoid, a more effective approach is to focus on the foods you can add—particularly those rich in unsaturated fats.
What are Unsaturated Fats?
Unsaturated fatty acids include monounsaturated fats (MUFA) and polyunsaturated fats (PUFA), including omega-3 and omega-6 fatty acids.
These fats come from both plant and marine sources and play essential roles in cardiovascular and metabolic health.
In practical terms, these are often referred to as “healthy fats” because of their consistent association with improved heart health outcomes.
Monounsaturated Fats (MUFA)
Found in olive oil, avocados, almonds, pistachios, and other nuts. These fats support healthy cholesterol levels and improved vascular function.
Polyunsaturated Fats (PUFA)
This group includes both omega-6 and omega-3 fatty acids and is found in foods such as fatty fish, walnuts, flaxseeds, sunflower seeds, and many plant oils. PUFAs break down into additional categories.
Omega-6 fatty acids:
Commonly found in vegetable oils (soybean, canola, sunflower), nuts, and seeds. Linoleic acid (LA) is an essential omega-6 fat that must be obtained from diet.
Omega-3 fatty acids:
Found in fatty fish, algae, flaxseed, chia seeds, and walnuts.
EPA and DHA:
Marine-based omega-3s found primarily in salmon, sardines, anchovies, and herring. These are the omega-3s most strongly linked to heart health.
Alpha-linolenic acid (ALA):
A plant-based omega-3 found in walnuts, chia seeds, and flaxseeds. ALA can convert to EPA and DHA, though the conversion rate is low.

How Unsaturated Fats Support Heart Health
A growing body of research shows that diets rich in unsaturated fats provide measurable cardiovascular benefits. These include reduced inflammation, improved lipid profiles, lower triglycerides, and decreased risk of heart attack and stroke.
Nuts and Seeds: Small Daily Additions, Big Impact
A 2022 umbrella review of 23 meta-analyses showed that adding one daily serving of nuts or seeds (15–28 g) is associated with up to a 20 percent reduction in cardiovascular disease risk (Balakrishna et al., 2022).
These foods were also linked to a 10 percent lower risk of type 2 diabetes and a 40 percent reduction in diabetes-related mortality. Despite being calorie-dense, nut-enriched diets do not promote weight gain and consistently improve LDL-C, triglycerides, total cholesterol, and ApoB.
Omega-3 Fats From Fish Reduce Heart Attack Risk
Omega-3 polyunsaturated fatty acids from fish, especially EPA and DHA, are among the most studied heart-protective nutrients.
Regular fish intake lowers triglycerides and is associated with reduced risk of both fatal and nonfatal heart attacks (McMullan et al., 2023). Even modest increases, such as eating salmon twice per week, improve lipid markers in real-world settings (Utri-Khodadady et al., 2024).
MUFA and PUFA Intake Predict Better Long-Term Outcomes
Large cohort studies show that higher intake of MUFA (oleic acid) and PUFA (ALA, EPA, DHA, LA) is associated with:
- Better vascular health
- Lower blood pressure
- Reduced arterial stiffness
- Significantly lower rates of coronary heart disease
These long-term associations highlight how unsaturated fats influence cardiovascular health across decades (Del Gobbo et al., 2016).
The Practical Takeaway: What to Add to Your Diet
If you’re looking to improve heart health, focus on consistently adding:
- Olive oil
- Nuts and seeds
- Fatty fish (salmon, sardines)
- Flaxseed and chia seeds
Small, consistent additions of these foods can meaningfully improve lipid markers and long-term cardiovascular risk.
The Bottom Line
Increasing unsaturated fats from foods like olive oil, nuts, seeds, flax, salmon, and sardines is one of the most evidence-supported ways to improve cholesterol levels, reduce inflammation, and protect cardiovascular health.
The research consistently shows that focusing on these nutrient-rich foods provides measurable benefits without the need for strict dietary restriction.
About the Author
Joseph Lehrberg, MS, RD is a registered dietitian specializing in cardiovascular and metabolic health and founder of CardioFunction Integrative Nutrition Services, a nutrition practice based in Boston. He works with patients with elevated cholesterol, high coronary artery calcium scores, high triglycerides, statin intolerance, and other cardiometabolic risk factors to develop evidence-based nutrition strategies for long-term heart health.
Learn more about working with him here.
References
Balakrishna, R., et al. (2022). Nut consumption and cardiovascular outcomes: An umbrella review of meta-analyses. Nutrition Reviews, 80(7), 1564–1583.
McMullan, M., et al. (2023). Fish consumption, marine omega-3 fatty acids, and cardiovascular disease risk. Journal of the American Heart Association, 12(4), e028345.
Utri-Khodadady, F., et al. (2024). Effects of salmon consumption on lipid biomarkers in real-world dietary patterns. European Journal of Clinical Nutrition, 78, 112–120.
Del Gobbo, L., et al. (2016). Omega-3 and omega-6 fatty acid intake and cardiovascular outcomes. Circulation, 133(3), 252–264.



